Tigecycline

25 June 2023

Nature: Glycylcycline, a member of the tetracycline family. Semisynthetic derivative of minocycline.MW: 585.6 Mechanism of action: 1. Bind to 30S ribosomal subunit and inhibit protein synthesis – It inhibits the attachment of aminoacyl tRNA to the A site and prevents chain elongation, i.e. block the translation process.2. Inhibit mitochondrial protein synthesis by binding to 70 […]